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Genomic sequencing data show that Nimbus has appeared in multiple countries and has gained a foothold even in regions that previously reported relatively low infection rates. Stratus, or XFB, emerged slightly earlier and has demonstrated similar adaptability, establishing itself across diverse geographic areas. Although these mutations increase transmissibility, current evidence suggests they do not significantly elevate the risk of severe disease, particularly among individuals who are vaccinated or have received recent booster doses. This distinction is critical for public understanding. A virus that spreads more efficiently can still pose a serious societal challenge by infecting large numbers of people simultaneously, even if individual risk remains relatively low. High case counts can disrupt workplaces, schools, and essential services while increasing the likelihood that vulnerable individuals will be exposed.
Vaccination remains central to the strategy for managing the spread of Stratus and Nimbus. Health officials in both the UK and the US continue to encourage booster uptake, particularly as updated formulations are rolled out for the respiratory virus season.
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